Rowe PDF 108Kb

Prize-winning Translational Abstract:

In vitro Human enthesitis model with induced IL17A and TNFα from CD4+ and CD8+ lymphocytes and effect of pharmacological antagonism with Janus Kinase and retinoic acid receptor-related orphan receptor γ inhibition.

H.Rowe¹, A. Watad^1,2,3, C. Bridgewood¹,  T. Russell¹, D.Newton¹, M.Wittman^1,4, Q. Zhou^1,5, A. Khan⁶, R. Dunsmuir⁶, P. Loughenbury⁶  R. Cuthbert¹, and D. McGonagle¹

1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; 2Department of Medicine ‘B’ Zabludowicz Centre for Autoimmune Diseases, Sheba Medical Centre, Tel-Hashomer, Israel; 3Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel;  4National Institute of Health Research (NIHR) Leeds Biomedical Research Centre (BRC), Leeds Teaching Hospital, Leeds, UK;  5Department of Rheumatology, Sichuan, Provincial People’s Hospital, Chengdu, China; 6 The Leeds Teaching Hospital, NHS Trust, Leeds, UK.