Professor Thomas Carell

• Professor of Organic Chemistry Ludwig-Maximilians-Universität München
• Email: Thomas.Carell@cup.uni-muenchen.de
• Telephone: +49 (0)89 2180 77750
• Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, Germany

The Carell group uses modern synthetic organic chemistry to synthesize naturally occurring modified DNA and RNA bases. These may be bases that are generated as part of a genetic system beyond the DNA sequence code to program the activity of the genome in different cell types. These DNA bases are of fundamental importance for cellular differentiation and de-differentiation, which is the reason the Carell group operates a stem cell laboratory. They are synthesizing DNA lesions and study how these lesions lead to cellular degeneration and how cells are able to repair these DNA lesions.